effect on the blood pressure. The antidiuretic action of pituitary extract is probably due entirely to vasopressin, but may be due to a third as yet unrecognized principle. Pituitary extract antagonizes the internal secretion of the pancreas- insulin. Hyperpituitarism or increased secretion of the pituitary gland causes gigantism and acromegaly; increased sexual excitement, glycosuria, profuse sweating and connective tissue hyperplasia. Hypopituitarism or diminished activity of the pituitary causes depression of the sexual function; changes in the skin and hair; adiposity, stunted skeletal development, mental backwardness, lowered basal metabolic rate (about 20 per cent below normal). SUPRARENAL (ADRENAL): This gland consists of the external cortex and internal medulla. The physiological functions of the secretions are obscure. The cortex is essential to life, the medulla is not. The medulla secrets epinephrine. Extracts obtained from the cortex apparently influence favorably the symptoms of Addisons disease. There is no doubt that the secretion of the adrenals has many functions, among these is perhaps the prevention of undue relaxation of the arteries, thereby maintaining normal blood pressure. This action becomes markedly accentuated in violent excitement, such as fear or rage. In some respects the action of the adrenal secretion is antagonistic to that of the thyroid, and it is quite possible that a proper balance between the two is necessary to maintain normal conditions in the body. Addisons disease, which heretofore has been considered a condition resulting from underaction of the adrenal medulla, is, in view of its successful treatment by extract from the cortex, most probably a result of hyposecretion of the cortex. TESTIS (TESTICLE): The male sex gland. The effect of the testicular secretion can only be conjectured from the results following castration. If the tests are removed before puberty, the rest of the reproductive apparatus does not develop; the seminal vesicles and the prostate are small and atrophic. The secondary sex characters do not appear. There is no growth of hair on the face, trunk, or axillae; the pubic hair if of the female type; the growth of the larynx is arrested. The mentality is peculiar and marked depression is often present. There is a tendency to gigantism. There may be abnormal deposition of fat. After puberty, no skeletal changes occur, but the condition is similar to the already described. The penis, however, remains of normal size. Sexual feeling is usually lost, though an imperfect erection of the penis may sometimes occur. THYMUS: The thymus continues to enlarge until the age of puberty. After the fourteenth to sixteenth year it steadily becomes smaller, and atrophies at 50 to 60 years of age. Probably regulates the growth of the child. Persistence of the thymus after puberty may lead to a condition designated as status thymo-lymphaticus. It is stated that sudden deaths are due to this condition. Injected of the extract obtained from the thymus lowers the arterial pressure and accelerates the heart beat. Status lymphaticus may give rise to female sexual characteristics in the male, and to sexual underdevelopment in the female. Substance Occurrence in the body Function in the body WATER Fluid medium in all body fluids, blood, lymph, digestive juices, secretions of the body; in all cells, fluids bathing cells, heart muscles, etc. Furnishes fluid medium for all body excretions and secretions, prevents friction, assists in elimination, digestion, metabolism. Element Source in flood Daily requirements SODIUM As sodium chloride (NaCl) is all foods except pure fats and carbohydrates. Average diet sufficient. Requirements from 1 12 to 2 grams a day. POTASSIUM Lean meat, milk, most plants. Average diet sufficient. CALCIUM Milk, cheese, nuts, cereals, vegatables. Adults, 0.68 to 1 gram. Children 1 gram or more. MAGNESIDUM Cereals, potatoes, most plants. Adequate in aver diet. PHOSPHORUS Milk, meat, egg yolk, nuts, vegetable, fruits. Adults 1.32 grams. Children 1 gram or more. CHLORINE As sodium in all foods except pure fats, pure carbohydrates. Intake sufficient in average diet. IODINE Sea food, marine algae, certain plants. About 5 milligrams a year for adults. IRON Glandular organs: liver, kidney, gizzard, egg yolk; green vegetables, spinach in particular; fruits: dried apricots, peaches, raisins, etc. Whole grain cereals. Adults, 15 milligrams; during pregnancy and lactation, 22 milligrams. Children, 7 12 to 10 12 milligrams per 1000 calories. SULFUR Chiefly protein foods. Diet adequate in protein is adequate in sulfur. WATER As water, fruit juices, milk; all fruits except those dehydrated or artificially dried. 6 to 8 glasses daily in addition to that supplied in food.